{"product_id":"9781588291998","title":"Molecular Neurosurgery with Targeted Toxins","description":"Pioneers and leading researchers explain the theory and techniques of using targeted toxins experimentally. The highly successful use of the 192 IgG-saporin and ME20.4-saporin immunotoxins to lesion the cholinergic basal forebrain in order to model the behavior, anatomy, physiology, and pharmacology of Alzheimer's disease in animals is treated in detail to give a potential user the knowledge to comfortably use the techniques involved. The uses of important new lesioning agents such as anti-DBH-saporin immunotoxin to make remarkably selective lesions of catecholaminergic neurons, hypocretin-saporin that can produce narcoleptic animals, and other saporin conjugates, such as neuropeptide-saporin conjugates for pain research and cholera toxin B chain-saporin to produce a model of CNS demyelination are explained by experts in the field.","brand":"Ronald G. Wiley","offers":[{"title":"Default Title","offer_id":46947362963774,"sku":"9781588291998","price":6165.8,"currency_code":"ZAR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0784\/4357\/7662\/products\/9781588291998_07d3c22d-88cb-4779-b31a-ab5b9de884a1.jpg?v=1707560783","url":"https:\/\/exclusivebooks.co.za\/products\/9781588291998","provider":"Exclusive Books Online","version":"1.0","type":"link"}