Authoritative Guide to Chronic Pediatric Abdominal Pain

An Authoritative Guide to Chronic Pediatric Abdominal Pain: Pathophysiology, Diagnosis and Management provides a comprehensive and extensive overview of all aspects relevant to the care of children with abdominal pain. It includes chapters tailored to each discipline, level of training, and primary interest (clinical or research), covering daily practice, diagnosis, testing, conventional and complementary treatments, interdisciplinary care, and the transition to adult gastroenterology treatment. The book critically updates the evidence behind these methods and prepares readers to understand more advanced techniques. Topics include early adverse life events, intestinal permeability, visceral hypersensitivity, sex differences, microbiome infections, use of antibiotics, and the microbiome.Information on clinical perspectives and management in the emergency department helps inform pediatricians, gastroenterologists, residents, fellows, and nurse practitioners about the scientific basis for prior workups, differential diagnoses, and the rationale behind them. In addition, this book helps clinicians understand the basic research behind these factors, how they influence pathophysiology, clinical presentation, progression, and outcomes.

Miguel Saps MD, a pediatric gastroenterologist, is the Chief of Division Pediatric Gastroenterology, Hepatology, and Nutrition at Holtz Children’s Hospital of Miami. He holds the George E. Bachelor Chair in Pediatrics and is a Professor of Pediatrics at the University of Miami. With a background in pediatric motility disorders, Dr. Saps has held key positions at renowned medical institutions, including Nationwide Children’s Hospital and Lurie Children’s Hospital. He has contributed significantly to research, with over 150 peer-reviewed articles and numerous presentations globally. Dr. Saps is actively involved in various committees and advisory boards, such as the FDA Gastrointestinal Advisory Drug Committee and the Pediatric Rome Committee. His mentorship has shaped the careers of pediatric gastroenterologists and motility experts worldwide. Marc Benninga MD, PhD is a Professor of Paediatrics specializing in paediatric gastroenterology at the University of Amsterdam’s Faculty of Medicine (AMC-UvA). He has been a key figure at the Paediatric Gastrointestinal Department of the Emma Children’s Hospital AMC since 2001, serving as department head since 2007. Dr. Benninga's research focuses on the etiology of functional gastrointestinal conditions such as gastroesophageal reflux disease, chronic abdominal pain, constipation, and fecal incontinence.He coordinates and conducts large-scale clinical trials to evaluate new medications and the effectiveness of nutritional supplements like pre and probiotics. He serves on the editorial boards of Neurogastroenterology and Motility, and Digestive and Liver Disease, and chairs the European Society for Paediatric Gastroenterology, Hepatology and Nutrition’s Motility and Paediatric Functional GI Disorders working group. He has secured over €700,000 in grants to study hypnotherapy's effectiveness in treating chronic abdominal pain and irritable bowel syndrome.