Fever and Antipyresis

This book provides a detailed overview of the function of the nervous system in fever and its role in antipyresis. The volume opens with an introductory account of fever, its physiology and adaptive role, and explains the mechanisms of thermoregulation. Sufficient information about bacterial pyrogens, 'endogenous' pyrogenic cytokines, body temperature regulation and survival value of fever and its ubiquity is given to enable readers to follow the central nervous system's involvement. The book should enable graduate students and researchers in neuroscience and other disciplines to understand the impact of their studies in the overall processes of fever. It will also be of benefit to pharmacologists studying anti-pyretics and the central nervous system function of these drugs. Academic clinicians will find this a more comprehensive overview of fever than other available texts. Finally, the author challenges some well-established dogmas in this area and sets an agenda for future research.

"Concise and comprehensive....Anyone who has ever pondered the topic of fever will find this book intriguing and informative. In this regard, the work has wide appeal. Graduate students in physiology--particularly if their area of research is fever, thermoregulation, or the hypothalamus--will consider this publication a gem." William C. Halliday, Annals RCPSC, "This careful work encompasses over 30 years of work dedicated to the topic. It is a judicious account of a facet of medicine and neurology that interfaces with us all on both a personal and professional level." John Tibbles, Canadian Journal of Neurological Sciences, "...this excellent and useful volume is rounded off with the author's synthesis of the material presented and what it means, along with his own provocative and stimulating speculations on where future research in this exciting field might lead." John T. Stitt, The Quarterly Review of Biology