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    Advances in DNA Repair in Cancer Therapy

Advances in DNA Repair in Cancer Therapy

Lawrence Panasci
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      FORMAT: Hardback

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      ​A comprehensive review of the recent developments in DNA repair research that have potential for translational applications. The book explains in detail the various biological mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the impact of such novel inhibitors of DNA repair mechanisms as methylguanine-DNA-methyltransferase. Also examined are inhibitors of other DNA repair enzymes such as PARP and DNA-PK. The book captures-for both cancer researchers and oncologists dealing with hallmark "relapse" or "drug resistance" phenomena on a daily basis-the many exciting new uses of DNA repair inhibitors, either alone or in combination with anticancer therapies.​
      Format: Hardback CONTRIBUTORS: Lawrence Panasci EAN: 9781461447405 COUNTRY: United States PAGES: WEIGHT: 6033 g HEIGHT: 235 cm
      PUBLISHED BY: Springer-Verlag New York Inc. DATE PUBLISHED: 2012-12-06 CITY: GENRE: MEDICAL / Oncology / General, SCIENCE / Life Sciences / Molecular Biology WIDTH: 155 cm SPINE:

      Book Themes:

      Medical research, Oncology

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      ​A comprehensive review of the recent developments in DNA repair research that have potential for translational applications. The book explains in detail the various biological mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the impact of such novel inhibitors of DNA repair mechanisms as methylguanine-DNA-methyltransferase. Also examined are inhibitors of other DNA repair enzymes such as PARP and DNA-PK. The book captures-for both cancer researchers and oncologists dealing with hallmark "relapse" or "drug resistance" phenomena on a daily basis-the many exciting new uses of DNA repair inhibitors, either alone or in combination with anticancer therapies.​
      Format: Hardback CONTRIBUTORS: Lawrence Panasci EAN: 9781461447405 COUNTRY: United States PAGES: WEIGHT: 6033 g HEIGHT: 235 cm
      PUBLISHED BY: Springer-Verlag New York Inc. DATE PUBLISHED: 2012-12-06 CITY: GENRE: MEDICAL / Oncology / General, SCIENCE / Life Sciences / Molecular Biology WIDTH: 155 cm SPINE:

      Book Themes:

      Medical research, Oncology

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