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Myeloid Leukemia

Harry Iland
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      A panel of internationally recognized research scientists and clinical investigators brings together a diverse collection of readily reproducible methods for identifying and quantifying a large number of specific genetic abnormalities associated with the broad spectrum of myeloid malignancies. Highlights include techniques for the detection of BCR-ABL mutations and resistance to imatinib mesylate, detection of the FIP1L1-PDGFRA fusion in idiopathic hypereosinophilic syndrome and chronic eosinophilic leukemia, classification of AML by DNA-oligonucleotide microarrays, and detection of the V617F JAK2 mutation in myeloproliferative disorders. In addition to gene rearrangments, other prognostically relevant molecular lesions such as FLT3 mutations and WT-1 overexpression are covered.
      Format: Hardback CONTRIBUTORS: Harry Iland EAN: 9781588294852 COUNTRY: United States PAGES: WEIGHT: 705 g HEIGHT: 235 cm
      PUBLISHED BY: Humana Press Inc. DATE PUBLISHED: 2005-11-15 CITY: GENRE: MEDICAL / Hematology WIDTH: 155 cm SPINE:

      Book Themes:

      Haematology

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      A panel of internationally recognized research scientists and clinical investigators brings together a diverse collection of readily reproducible methods for identifying and quantifying a large number of specific genetic abnormalities associated with the broad spectrum of myeloid malignancies. Highlights include techniques for the detection of BCR-ABL mutations and resistance to imatinib mesylate, detection of the FIP1L1-PDGFRA fusion in idiopathic hypereosinophilic syndrome and chronic eosinophilic leukemia, classification of AML by DNA-oligonucleotide microarrays, and detection of the V617F JAK2 mutation in myeloproliferative disorders. In addition to gene rearrangments, other prognostically relevant molecular lesions such as FLT3 mutations and WT-1 overexpression are covered.
      Format: Hardback CONTRIBUTORS: Harry Iland EAN: 9781588294852 COUNTRY: United States PAGES: WEIGHT: 705 g HEIGHT: 235 cm
      PUBLISHED BY: Humana Press Inc. DATE PUBLISHED: 2005-11-15 CITY: GENRE: MEDICAL / Hematology WIDTH: 155 cm SPINE:

      Book Themes:

      Haematology

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