Evidence-based Management of Lipid Disorders

Practising evidence-based medicine necessarily depends on the clinician having access to the best evidence available, but in a fast-moving field, keeping up to date with the latest developments is a challenging prospect. In this new volume, leading experts focus on the most important clinical issues associated with the management of Lipid Disorders, evaluating and interpreting the evidence available to provide the reader with a reliable summary of our current knowledge. Topics covered include therapeutic strategies for managing hereditary lipid disorders, including familial hypercholesterolaemia, both in adults and children, and familial combined hypercholesterolaemia. The authors also evaluate the evidence for a link between inflammatory disease and cardiovascular risk; the metabolic syndrome and the interconnections between dyslipidaemias and diabetes. They also look at therapeutic challenges such as the management of patients who are statin resistant, and the control of lipid levels in those suffering renal insufficiency. Tables highlight important data, evidence from trial results and expert reports, and each section concludes with a series of Key Points that present a summary of evidence-based recommendations for best practice, graded according to the quality of that evidence. The book provides the busy clinician with a unique analysis of the data supporting current therapies and will help the reader formulate effective strategies for treating their own patients.

Maud N Vissers PhD, Academic Medical Centre, Department of Vascular Medicine, University of Amsterdam, Amsterdam, The Netherlands John JP Kastelein MD PhD, Academic Medical Centre, Department of Vascular Medicine, University of Amsterdam, Amsterdam, The Netherlands Erik S Stroes MD PhD, Academic Medical Centre, Department of Vascular Medicine, University of Amsterdam, Amsterdam, The Netherlands