Practical Gas Chromatography

Gas chromatography continues to be one of the most widely used analytical techniques, since its applications today expand into fields such as biomarker research or metabolomics. This new practical textbook enables the reader to make full use of gas chromatography. Essential fundamentals and their implications for the practical work at the instrument are provided, as well as details on the instrumentation such as inlet systems, columns and detectors. Specialized techniques from all aspects of GC are introduced ranging from sample preparation, solvent-free injection techniques, and pyrolysis GC, to separation including fast GC and comprehensive GCxGC and finally detection, such as GC-MS and element-specific detection. Various fields of application such as enantiomer, food, flavor and fragrance analysis, physicochemical measurements, forensic toxicology, and clinical analysis are discussed as well as cutting-edge application in metabolomics is covered.

“This textbook is worth reading by beginners in the fields of GC as well as those advanced users looking for inspiration in GC applications. In any library used by analytical scientists, this textbook is a must. It is an ideal combination of theory and practice written and edited by passionate chromatographers. … the book is worth buying and it may serve as your reference in practical GC analysis.” (Martin Vogel, Analytical and Bioanalytical Chemistry, Vol. 408 (29), November, 2016) “This is a mammoth work and one must congratulate the editors on the result of their task. … all users of GC will learn a lot from this book and, no matter how expert, they will find new and relevant information on their own specific problems.” (Edward R. Adlard, Chromatographia, Vol. 78, 2015)

Katja Dettmer-Wilde is Principal Investigator heading the mass spectrometry - metabolomics group at the Institute of Functional Genomics, University of Regensburg, Germany. She studied chemistry at the University of Leipzig and got her PhD with Werner Engewald working on the analysis of volatile organic compounds by GC-MS. Since her postdoctoral studies at the University of California Davis she has been focusing on hyphenated separation techniques in metabolomics. Werner Engewald is professor emeritus of the University of Leipzig, Germany. He is one of the leading gas chromatographers worldwide and has made substantial contributions towards the development of this technique. He regularly gives courses for GC users. He was awarded the Martin gold medal of the Chromatographic Society in 2002 and the Clemens-Winkler-Medal of the Division of Analytical Chemistry of the German Chemical Society in 2009.