Modeling and Simulation in Ecotoxicology with Applications in MATLAB and Simulink

Exploring roles critical to environmental toxicology, Modeling and Simulation in Ecotoxicology with Applications in MATLAB® and Simulink® covers the steps in modeling and simulation from problem conception to validation and simulation analysis. Using the MATLAB and Simulink programming languages, the book presents examples of mathematical functions and simulations, with special emphasis on how to develop mathematical models and run computer simulations of ecotoxicological processes.Designed for students and professionals with little or no experience in modeling, the book includes: General principles of modeling and simulation and an introduction to MATLAB and SimulinkStochastic modeling where variability and uncertainty are acknowledged by making parameters random variablesToxicological processes from the level of the individual organism, with worked examples of process models in either MATLAB or SimulinkToxicological processes at the level of populations, communities, and ecosystemsParameter estimation using least squares regression methodsThe design of simulation experiments similar to the experimental design applied to laboratory or field experimentsMethods of postsimulation analysis, including stability analysis and sensitivity analysisDifferent levels of model validation and how they are related to the modeling purposeThe book also provides three individual case studies. The first involves a model developed to assess the relative risk of mortality following exposure to insecticides in different avian species. The second explores the role of diving behavior on the inhalation and distribution of oil spill naphthalene in bottlenose dolphins. The final case study looks at the dynamics of mercury in Daphnia that are exposed to simulated thermal plumes from a hypothetical power plant cooling system. Presented in a rigorous yet accessible style, the methodology is versatile enough to be readily applicable not only to environmental toxicology but a range of other biological fields.

Dr. Kenneth R. Dixon’s current research interests include developing and applying computer simulation models to predict the movement of toxic chemicals in the environment and their effects on human and wildlife populations. He also studies the spatial distribution of toxicants and effects at ecosystem, landscape, and regional scales by integrating models with geographic information systems. Current research projects include developing food-chain models to predict the uptake and effects of pesticides, perchlorate, and explosives; developing spatial models of the spread of infectious diseases; and a mathematical programming model of the effects of pollutants on optimal feeding strategies. Dr. Dixon has taught courses in modeling, geographic information systems, ecosystems analysis, biometry, and wildlife management.