Atherothrombosis in Clinical Practice

Atherothrombosis refers to the coupling of atherosclerosis and thrombosis, and it is the leading cause of the majority of preventable deaths in the modern world. The medical, economic, social, and societal consequences or atherothrombosis are enormous, which make it a dynamic area for development of new pharmacologic agents. Atherothrombosis in Clinical Practice focuses upon the many clinical manifestations of atherothrombosis and therapies that presently exist, witha focus on evolving therapeutic approaches. First, atherothrombosis is defined and the epidemiology is explored. Then, the specific manifestations of atherothrombosis (coronary artery disease, valvular heart disease, cerebrovascular disease, atrial fibrillation, peripheral artery disease) areconcisely covered by distinguished experts in the field. Next, specific medications are discussed, with an emphasis on innovative therapies and investigational agents including experimental lipid-modifying, anti-inflammatory, antiplatelet, and anticoagulant agents. State-of-the-art treatment of hypertension and diabetes is described succinctly. Lifestyle modification, medical therapies, and where appropriate, invasive modalities are discussed. Controversies in areas such as cholesterolmanagement and glycemic control are summarized. Part of the Oxford American Cardiology Library, this handbook provides a practical, evidence-based summary of the condition and the most up-to-date research to equip clinicians in managing this common clinical problem.

This book is helpful enough to become a staple for clinicians who treat patients with atherothrombotic disease. It is one that I could read many times over to improve my recall of the evidence I use to treat patients daily.

Chief of Cardiology, VA Boston Healthcare System; Director, Integrated Interventional Cardiovascular Program, Brigham & Women's Hospital and VA Boston Healthcare System; Associate Professor of Mdicine, Harvard Medical School, Boston, Massachusetts