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Generating Evidence for Genomic Diagnostic Test Development

Institute of Medicine
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      Ten years after the sequencing of the human genome, scientists have developed genetic tests that can predict a person's response to certain drugs, estimate the risk of developing Alzheimer's disease, and make other predictions based on known links between genes and diseases. However, genetic tests have yet to become a routine part of medical care, in part because there is not enough evidence to show they help improve patients' health.The Institute of Medicine (IOM) held a workshop to explore how researchers can gather better evidence more efficiently on the clinical utility of genetic tests. Generating Evidence for Genomic Diagnostic Test Development compares the evidence that is required for decisions regarding clearance, use, and reimbursement, to the evidence that is currently generated. The report also addresses innovative and efficient ways to generate high-quality evidence, as well as barriers to generating this evidence.Generating Evidence for Genomic Diagnostic Test Development contains information that will be of great value to regulators and policymakers, payers, health-care providers, researchers, funders, and evidence-based review groups.Table of ContentsFront Matter1 Introduction2 Stakeholder Perspectives on Evidence3 Approaches to Evidence Generation4 Overcoming Barriers for Evidence Generation5 Considerations Moving Forward6 Final RemarksReferencesAppendix A: Workshop AgendaAppendix B: Speaker Biographical SketchesAppendix C: Registered Attendees
      Format: Paperback / softback CONTRIBUTORS: Institute of Medicine EAN: 9780309211048 COUNTRY: United States PAGES: WEIGHT: 0 g HEIGHT: 229 cm
      PUBLISHED BY: National Academies Press DATE PUBLISHED: 2011-07-27 CITY: GENRE: WIDTH: 152 cm SPINE:

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      Ten years after the sequencing of the human genome, scientists have developed genetic tests that can predict a person's response to certain drugs, estimate the risk of developing Alzheimer's disease, and make other predictions based on known links between genes and diseases. However, genetic tests have yet to become a routine part of medical care, in part because there is not enough evidence to show they help improve patients' health.The Institute of Medicine (IOM) held a workshop to explore how researchers can gather better evidence more efficiently on the clinical utility of genetic tests. Generating Evidence for Genomic Diagnostic Test Development compares the evidence that is required for decisions regarding clearance, use, and reimbursement, to the evidence that is currently generated. The report also addresses innovative and efficient ways to generate high-quality evidence, as well as barriers to generating this evidence.Generating Evidence for Genomic Diagnostic Test Development contains information that will be of great value to regulators and policymakers, payers, health-care providers, researchers, funders, and evidence-based review groups.Table of ContentsFront Matter1 Introduction2 Stakeholder Perspectives on Evidence3 Approaches to Evidence Generation4 Overcoming Barriers for Evidence Generation5 Considerations Moving Forward6 Final RemarksReferencesAppendix A: Workshop AgendaAppendix B: Speaker Biographical SketchesAppendix C: Registered Attendees
      Format: Paperback / softback CONTRIBUTORS: Institute of Medicine EAN: 9780309211048 COUNTRY: United States PAGES: WEIGHT: 0 g HEIGHT: 229 cm
      PUBLISHED BY: National Academies Press DATE PUBLISHED: 2011-07-27 CITY: GENRE: WIDTH: 152 cm SPINE:

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