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Experimental Models of Parkinson’s Disease

Yuzuru Imai
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      This detailed book focuses on cutting-edge methods for Parkinson’s disease (PD) research, such as the analysis of the prion-like properties of α-synuclein, mitochondrial functions related to the PINK1-Parkin pathway/CHCHD2, the endolysosome pathway related to LRRK2, VPS35, and ATP13A2 using cultured cells (including patient iPS cells), deep brain stimulation therapy, classic mitochondrial toxins related to PD, and genetic associations and screenings using mammalian and invertebrate genetic models of PD. The collection intends to serve as an introductory protocol book for basic research on PD pathogenesis. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Experimental Models of Parkinson's Disease is an ideal guide for researchers continuing to work toward making PD risk predictable and surmountable.
      Format: CONTRIBUTORS: Yuzuru Imai EAN: 9781071614945 COUNTRY: United States PAGES: WEIGHT: 642 g HEIGHT: 254 cm
      PUBLISHED BY: Springer-Verlag New York Inc. DATE PUBLISHED: 2021-05-28 CITY: GENRE: MEDICAL / Neuroscience, SCIENCE / Life Sciences / Biology WIDTH: 178 cm SPINE:

      Book Themes:

      Medical research, Neurology and clinical neurophysiology, Neurosciences

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      This detailed book focuses on cutting-edge methods for Parkinson’s disease (PD) research, such as the analysis of the prion-like properties of α-synuclein, mitochondrial functions related to the PINK1-Parkin pathway/CHCHD2, the endolysosome pathway related to LRRK2, VPS35, and ATP13A2 using cultured cells (including patient iPS cells), deep brain stimulation therapy, classic mitochondrial toxins related to PD, and genetic associations and screenings using mammalian and invertebrate genetic models of PD. The collection intends to serve as an introductory protocol book for basic research on PD pathogenesis. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Experimental Models of Parkinson's Disease is an ideal guide for researchers continuing to work toward making PD risk predictable and surmountable.
      Format: CONTRIBUTORS: Yuzuru Imai EAN: 9781071614945 COUNTRY: United States PAGES: WEIGHT: 642 g HEIGHT: 254 cm
      PUBLISHED BY: Springer-Verlag New York Inc. DATE PUBLISHED: 2021-05-28 CITY: GENRE: MEDICAL / Neuroscience, SCIENCE / Life Sciences / Biology WIDTH: 178 cm SPINE:

      Book Themes:

      Medical research, Neurology and clinical neurophysiology, Neurosciences

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