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Scaffolds for tissue engineering are devices that exploit specific and complex physical and biological functions, in vitro or in vivo, and communicate through biochemical and physical signals with cells and, when implanted, with the body environment. Scaffolds are produced mainly with synthetic materials, and their fabrication technologies are derived from already well-established industrial processes, with some new specific technologies having been developed in the last years to address required complexities.Often, a generalist approach is followed for the translation of materials and technologies designed for other applications, without considering the specific role of scaffolds from a physical and biological point of view. The book illustrates scaffold design principles, with particular relevance to the biological requirements needed to control and drive the biological cross talk, and reviews materials and fabrication and validation methods.
"This comprehensive textbook begins with chapters covering the structural and functional biology of body tissues, their healing processes, and their regeneration and ends with a chapter looking toward the future commercialization of tissue-engineered scaffolds. It should be useful for those doing research on tissue-engineered scaffolds, companies developing tissue-engineered products, and clinicians looking to the future replacement of tissues in the clinic."Prof. Allan S. Hoffman, University of Washington, USA"The current volume provides an excellent basis to assist researchers in leaving the path of trial and error and designing scaffolds on the basis of true understanding. It is a must-read for anybody interested in tissue engineering."Prof. Clemens A. van Blitterswijk, University of Twente, the Netherlands"Tissue engineering is the most promising technology to treat various diseases by using cultured cells and will be a main actor in medical science in the twenty-first century. The fusion of medicine and engineering is essentially indispensable for tissue engineering, especially scaffold-based tissue engineering. This very timely book will be equally useful for those who have engineering, medical, and biological science background."Prof. Teruo Okano, Tokyo Women’s Medical University, Japan
Claudio Migliaresi is professor of composite materials engineering and of biomaterials and biomedical technologies, head of the Department of Industrial Engineering, dean of the School of Industrial Engineering, and head of the BIOtech Research Center of the University of Trento, Italy. His research activities range from composite materials to biodegradable polymers, biomaterials, materials, and scaffolds for tissue engineering. Prof. Migliaresi has published about 200 papers, edited the five volumes of the book Polymers in Medicine, and owns some patents. Antonella Motta is assistant professor at the University of Trento and has qualified as associate professor of bioengineering by the Italian evaluation system. She teaches bioengineering and tissue engineering and regenerative medicine courses. Prof. Motta’s research activities are mainly focused on nature-derived polymers for tissue engineering applications, scaffold design, and interactions of material–biological systems. She has published about 90 papers, edited several chapters on tissue engineering, and owns some patents.
Scaffolds for tissue engineering are devices that exploit specific and complex physical and biological functions, in vitro or in vivo, and communicate through biochemical and physical signals with cells and, when implanted, with the body environment. Scaffolds are produced mainly with synthetic materials, and their fabrication technologies are derived from already well-established industrial processes, with some new specific technologies having been developed in the last years to address required complexities.Often, a generalist approach is followed for the translation of materials and technologies designed for other applications, without considering the specific role of scaffolds from a physical and biological point of view. The book illustrates scaffold design principles, with particular relevance to the biological requirements needed to control and drive the biological cross talk, and reviews materials and fabrication and validation methods.
Claudio Migliaresi is professor of composite materials engineering and of biomaterials and biomedical technologies, head of the Department of Industrial Engineering, dean of the School of Industrial Engineering, and head of the BIOtech Research Center of the University of Trento, Italy. His research activities range from composite materials to biodegradable polymers, biomaterials, materials, and scaffolds for tissue engineering. Prof. Migliaresi has published about 200 papers, edited the five volumes of the book Polymers in Medicine, and owns some patents. Antonella Motta is assistant professor at the University of Trento and has qualified as associate professor of bioengineering by the Italian evaluation system. She teaches bioengineering and tissue engineering and regenerative medicine courses. Prof. Motta’s research activities are mainly focused on nature-derived polymers for tissue engineering applications, scaffold design, and interactions of material–biological systems. She has published about 90 papers, edited several chapters on tissue engineering, and owns some patents.
Die verhaal van die kasarm en die Calitze kom tot 'n mooi einde
Ek kan nie ’n boek summier toemaak nadat die slotsin geskryf is nie. Ek lees álles, tot by die outeursnotas en die bronnelys (gewoonlik gooi ek darem net vlugtig ’n oog oor die bonne!). Chanette Paul maak in die nota oor Maanschijnbaai 2, die verdere verhaal van Nan en Jeannie, die stelling: “Lesers moet my asseblief vergewe dat my verbeelding altyd die oorhand oor die werklikheid kry en verdigsel voorkeur bo feite.” (p.635) Ek wil daarby aanhaak en bieg dat ’n uitstekende verhoudingsroman soos hierdie tydelik die oorhand gekry het oor my traagheid om te lees oor reïnkarnasie en die esoteriese. Die klomp Calitzse het my tyd en aandag totaal gekaap.
Die skrywer wy die laaste bladsye aan ’n verduideliking oor hoe die Maanschijnbaai-tweeluik ontstaan het. Sy beweer dat die Calitze haar “onkant” betrap het. Sy wou ’n romanse skryf maar uiteindelik was die karakters so kompleks dat dit op twee dik boeke en ’n intense familiedrama uitgeloop het.
Van die onderskeie karakters raak diep waarhede kwyt wat die moeite werd is om te onderstreep en te onthou, soos Zach wat dit gehad het oor die risiko om iemand op ’n pedestal te plaas omdat jy daardeur die persoon ’n onreg aandoen. (p.539) En Nan, wat die hele klomp Calitze moes grootkry, se wyse raad: “Met eerlikheid, Jeannie, kom ’n mens baie verder as met opoffering. Met eerlikheid gee jy almal ’n regverdige kans. Opoffering beteken bloot jy doen iets teen jou sin omdat jy glo dit sal ander baat.” (p.613)
Maak seker dat jy genoeg tyd op hande het, dan lees jy hierdie tweeluik in volgorde, Jo & Sue, gevolg deur Nan & Jeannie. Dit is hersien en met splinternuwe, pragtige baadjies uitgegee deur Lapa Uitgewers.
A very practical approach and the tools to go along with it
Very useful. The book provides a structure and an approach that I would have been useful earlier in my investing. I like the five gates and in particular the attention to quality and management's capital allocation decisions. I will also apply the idea of the stewardship log to get more explicit on my investment theses. This is kind of the practical aspect of what I learned from the Psychology of Money.
the title ties in really nicley the more towards the end but the title for the book suits it real...
the book is very slow burn and takes a while for like captivating parts of the book .but the middle to the end the pace of the book is really nice the beginning is just repetitive and and trust the processes
Skuld en vergifnis word nie versuiker in hierdie jeugverhaal nie
Twee halwes maak ’n hele is die wenner van ’n jeugboekprys. Ek moes myself gedurig herinner wat die teikenmark nou eintlik is, want die sake wat aangeraak word, is geensins beperk tot jeugdige lesers nie. Die sterk newe-karakters dra daartoe by die selfs baie ouer lesers goed aanklank kan vind by die storielyn wat ontvou.
“Hulle sê as jy iemand vergewe, lig jy ’n vrag van daardie persoon se skouers af. Maar miskien is sommige dinge net te swaar om van iemand anders se skouers te lig?” (p.178) Baie aandag word gegee aan skuld en vergifnis, maar geen suikeromhulde kitsoplossings word aangebied nie. Dit sou die storie beslis vervlak het.
Na die aardskuddende ontdekking wat Lira gemaak het, gaan sy vir drie maande na ’n Griekse eiland en maak sy kennis met haar ander helfte, ’n halfsuster wat presies die teenoorgestelde is van haar eie ingetoë, overthinking self. Ek het daarvan gehou dat hulle, die verskille ten spyt, nie in heftige konflik was nie. Eerder besig om algaande te ontdek dat hulle by mekaar kan aanpas en albei sterker daardeur kan kom.
Marita van der Vyver is ’n waardige wenner van die Tafelberg Jeugboekprys en hierdie boek hoort beslis in van der Vyver versamelings. Dit is uitgegee deur Tafelberg, ’n druknaam van Jonathan Ball Uitgewers.
